Genetic Association Study of IL2RA, IFIH1, and CTLA-4 Polymorphisms With Autoimmune Thyroid Diseases and Type 1 Diabetes
نویسندگان
چکیده
منابع مشابه
Association of CTLA-4 Polymorphisms with Type 1 Diabetes in the Egyptian Population
1The Egyptian Organization for Biological Products and Vaccines (EGYVAC-VACSERA), The Egyptian Ministry of Health and Population, Egypt 2Section Research, Department of Medical Genetics, University Medical Center Utrecht, The Netherlands 3Institute of Pathophysiology, Semmelweis University Medical School, Semmelweis University, Hungary 4Hungarian Academy of Sciences, Semmelweis University, Neph...
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BACKGROUND IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. METHODS AND RESULTS Here we perform a replication and fine mapping of the IL2RA gene region analyzing 3 SNPs previously associated with multiple sclerosis (MS) and 5 SNPs associated with type 1 diabetes (T1D) in a collection of 79...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Meta-analysis of STAT4 and IFIH1 polymorphisms in type 1 diabetes mellitus patients with autoimmune polyglandular syndrome type III.
Type 1 diabetes mellitus (T1D) is an organ-specific autoimmune disease characterized by T-cell mediated self-destruction of insulin-producing β cells in the pancreas. T1D patients are prone to develop other glandular autoimmune disorders, such as autoimmune thyroid disease that occurs simultaneously with autoimmune polyglandular syndrome type III (APSIII). Signal transducer and activator of tra...
متن کاملAssociation between C1q gene polymorphisms and autoimmune thyroid diseases.
OBJECTIVE In the present study, we aimed to assess the associations of C1q gene polymorphisms with autoimmune thyroid diseases (AITD) susceptibility. SUBJECTS AND METHODS A set of 1,003 AITD patients (661 with Graves' disease and 342 with Hashimoto's thyroiditis) and 880 ethnically- and geographically-matched controls from Chinese Han population were included. Five common single nucleotide po...
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ژورنال
عنوان ژورنال: Frontiers in Pediatrics
سال: 2020
ISSN: 2296-2360
DOI: 10.3389/fped.2020.00481